Hot/Cold Plate – Screening of Thermal Hyperalgesia/Allodynia
MANUFACTURER – UGO BASILE
PRODUCT CODE – 35300
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Description
Hot/Cold Plate – Screening of Thermal Hyperalgesia/Allodynia
Description Of Hot/Cold Plate – Screening of Thermal Hyperalgesia/Allodynia
Background
- Motor (or vocal) responses are normally the endpoints for thermal sensitivity tests and this has been true for hot temperatures and cold temperatures to study hyperalgesia and allodynia.
- More recently, the introduction of tamping devices, capable to increase the temperature from a starting point to an end point at given time rate, have largely improved the ability to differentiate between hyperalgesic and allodynic responses.
- The hot/cold plate method is a very traditional one and had the advantage of having unrestrained animals, however, a large variety in scoring methods can be found in the literature, and it depends on the visual scoring of the experimenter herself.
- Some labs use the first hind paw lick as test endpoints; others use the frequency of licks over a certain time window, other use jumping or vocalizations.
System components and main features
The Ugo Basile Hot/Cold Plate system comes complete with:
- An electronic unit with touch screen to set all parameters and save data
- The Perspex animal restrainer
- USB port to save data and export them in CSV files
- A NEW keypad to score endpoints or any other stereotyped behavior (bluetooth optional)
- A temperature ranges from -5° to 65°C
- A room ambient temperature sensor
- A very silent operation, even when the Peltier elements work at full speed to cool down the device quickly
- A NEW software on the touch screen with several new features, e.g. temperature in °C and °F, an online, an integrated help section, a stop or go option for the end of the ramp mode, a graph showing the plate temperature in real time and a new result screen which is clearer and more comprehensive
- The new software includes all the animal behaviors that can be scored with the 10 keys available
- A PC software to build custom temperature ramps and populate your animal vivarium
Additional features include:
- TTL input/outputs for start/stop and mode command
- USB port for PC connection
- COM port for maintenance purposes
- Ethernet port for support and maintenance (to be used at the factory only)
| Feature | Benefit |
|---|---|
| Fixed, ramping and complex ramp temperature modes | Flexibility for performing many types of pain experiments from allodynia to hyperalgesia |
| Keypad and pedal for scoring pain animal responses and stereotyped behaviors | Possibility to use the preset 10 keys or modify them (licking, scratching, jumping, grooming, vocalization, rearing, immobility, climbing, shivering, twitching) and save the results in the electronic unit |
| Broad range of temperatures (-5° to -65°) | Allows to perform any sort of thermal sensitivity experiment, including severe cold allodynia |
| Ambient temperature sensor is placed outside of the device | Improved system and thermal accuracy |
| Silent mode of operation or the air dissipation system | Less disturbance to the animal |
| Control unit and USB key saving | No need to connect a PC |
| Automatic conversion of data into CSV files for the USB stick | Possibility to open files in Excel |
| PC software | Possibility to populate your vivarium of animals and to build complex temperature ramps |
| General | |
|---|---|
| Commands | 4,3 inches touch-screen (Resistive) |
| Read-out | 4,3 inches touch-screen (Resistive), PC |
| Power Requirement | Universal input 100-240 VAC, 50-60Hz, 200W MAX |
| Sound Level | 70 dB |
| Operating Temperature | 18°C to 25°C |
| Detection | By pedal switch and via numeric key pad |
| Operation | |
| Plate temperature range | -5.0°C to +65°C (in 0.1°C steps) |
| Accuracy | +/- 0.2°C |
| Mode | Fixed temperature, Ramp (increasing or decreasing), Silent, Fast Ramp, Custom Ramp |
| Start | By START button or pedal switch |
| Stop | By STOP button or pedal switch |
| Experiment duration | Max 999.9 seconds |
| Data Acquisition | Via X-PAD software (included) |
| Data Portability | By USB flash drive (included) |
| Data Input | Personalized protocol |
| Data Output | Results table in .csv |
| TTL Output | Temperature, Start, Stop |
